Changxi Wang, People's Republic of China
Director
Organ Transplant Center
The First Affiliated Hospital of Sun Yat-sen University
Pathological analysis of 544 cases of indicated renal allograft biopsies
Xutao Chen1, Hongyang Wang 1, Wenfang Chen 2, Longshan Liu1, Qian Fu1, Jun Li1, Ronghai Deng 1, Changxi Wang 1.
1Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University , Guangzhou, People's Republic of China; 2Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University , Guangzhou, People's Republic of China
Objective: To explore the histopathological features and proportion of various renal allograft biopsies for post-transplant complications.
Methods: Between January 2010 and December 2015, 544 kidney transplants received 670 percutaneous renal allograft biopsies in our hospital. Pathological diagnosis and classification were performed according to the Banff 1997, 2007 and 2013 Schema.
Results: There were 22 (4.04%) cases of acute antibody—mediated rejection and 38 (6.99%) cases of acute T cell—mediated rejection in 544 kidney transplants. Besides, 54 (9.93%) cases were diagnosed as chronic antibody—mediated rejection and 18 (3.31%) cases as chronic T cell-mediated rejection. Acute CNI-nephrotoxicity and chronic CNI-nephrotoxicity were 43 (7.90%) cases and 31 (5.70%) cases, respectively. Relapsed or new-onset nephropathy were 111 (20.40%) cases, including 83 (15.26%) cases of IgA nephropathy. BK virus-associated nephropathy (BKVAN) was founded in 45 (8.27%) cases. There was no severe adverse effect after all renal allograft biopsies.
Conclusion: Percutaneous renal allograft biopsy is safe and contributes to the diagnosis and treatment of diverse post-transplant complications.
Lectures by Changxi Wang
| When | Session | Talk Title | Room |
|---|---|---|---|
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Sat-20 17:00 - 18:30 |
Kidney Posters | Hemodynamics in Transplant Renal Artery Investigated by Computational Fluid Dynamics | Hall 5FG-Level 5 |
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Sat-20 17:00 - 18:30 |
Kidney Posters | En Bloc Kidney Transplantation from Infant Donors Less Than 10 kg – surgical skill, clinical management and outcome in a transplant center in China | Hall 5FG-Level 5 |
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Sat-20 17:00 - 18:30 |
Kidney Posters | Pathological analysis of 544 cases of indicated renal allograft biopsies | Hall 5FG-Level 5 |
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Sat-20 17:00 - 18:30 |
Kidney Posters | Comparison of kidney transplantation from living and deceased donation: a consecutive data analysis since implement of donation after citizen’s death in China. | Hall 5FG-Level 5 |