P.1347 Kidney transplantation from pediatric donors of deceased organ donation
Saturday August 20, 2016 from 17:00 to 18:30
Hall 5FG-Level 5
Presenter

Chen Chuanbao, People's Republic of China

resident doctor

Third Division of Organ Transplant Center

East Campus of First Affiliated Hospital, Sun Yat-sen University

Abstract

Kidney transplantation from pediatric donors of deceased organ donation

Chen Chuanbao1, Yuan X. Peng1, Han Ming1, Wang X. Ping1, Zhou Jian1, Jiao X. Yuan1, Wang C. Xi2, He X. Shun1.

1Third Division of Organ Transplant Center, East Campus of First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China; 2Second Division of Organ Transplant Center, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, People's Republic of China

Objective: To explore the clinical effect of kidney transplantation from donation after citizen’s death (DCD) of pediatric donors.

Methods: The clinical data of kidney transplantation from DCD pediatric donors from February 2010 to October 2013 were retrospectively reviewed.

Result: There were 27 pediatric DCD donors with age of 10.5±5.2 years, including 19 males and 8 females, 16 cases of China category II and 11 cases of China category III. 6 cases of en bloc kidney transplantation and 42 cases of single kidney transplantation were performed. No primary non-function occurred. The incidence of delayed graft function, slow graft function and immediate graft function were 8.3%, 35.4% and 56.3%, respectively. Acute rejection occurred in 4 cases (8.3%). After follow-up of 5.2±6months, 1 renal graft lost due to antibody-mediated rejection, other grafts functioned well. The mean eGFR(estimated glomerular filtration rate)of adult recipients in 1 year was 76.1±17.7 ml•(min)-1•(1.73m2)-1.

Conclusion: The early clinical effect of kidney transplantation from pediatric donors after cardiac death is excellent. The pediatric DCD donors can be used to expand the donor pool.

Keywords: Kidney transplantation; Pediatric donors; Donation after cardiac death; En bloc kidney transplantation.


Lectures by Chen Chuanbao


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